The present invention provides a method for a topical treatment of a skin cyst. The method includes: applying a formulation to the skin cyst of a mammal wherein the formulation includes: a dimethyl sulfoxide extract of mature, dried, powdered Cannabis sativa flower and bud leaves, wherein the mature, dried, powdered Cannabis sativa flower and bud leaves include greater than or equal to about 10 weight percent of tetrahydrocannibolinic acid and have been heated for approximately five minutes at a temperature greater than or equal to about 160° C. to less than about 193° C.