A method for the treatment or prevention of a topical infection by a bacteria of the genusPropionibacteriumcomprising the step of: administering a therapeutically effective amount of a topical composition comprising a cannabinoid.一種治療或預防由丙酸桿菌屬細菌引起之局部感染之方法,其包括以下步驟:投與治療有效量之包含大麻素之局部組合物。