F. HOFFMANN-LA ROCHE AG;THE INSTITUTE OF CANCER RESEARCH;THE INSTITUTE OF CANCER RESEARCH : ROYAL CANCER HOSPITAL
发明人:
PAUL JOHN GOLDSMITH,TIMOTHY COLIN HANCOX,NEIL ANTHONY PEGG,STEPHEN JOSEPH SHUTTLEWORTH,JONATHAN MARTIN LARGE,EDWARD MCDONALD
申请号：
BRPI0811044
公开号：
BRPI0811044A2
申请日:
2008.04.14
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
The invention provides a pyrimidine compound of formula (I): wherein R1 and R2 have any of the values defined herein； or a pharmaceutically acceptable salt thereof. These compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
