F. Hoffmann-La Roche AG;The Institute of Cancer Research
发明人:
Edward Mcdonald,Elsa Amandine Dechaux,Jonathan Martin Large,Neil Anthony Pegg,Paul John Goldsmith,Stephen Joseph Shuttleworth,Stephen Price,Timothy Colin Hancox
申请号：
BRPI0810641
公开号：
BRPI0810641A2
申请日:
2008.04.14
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The invention provides a pyrimidine compound of formula (I): wherein R1, R2, and Y have any of the values defined herein； or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
