F. HOFFMANN-LA ROCHE AG;THE INSTITUTE OF CANCER RESEARCH
发明人:
STEWART JAMES BAKER,PAUL JOHN GOLDSMITH,TIMOTHY COLIN HANCOX,NEIL ANTHONY PEGG,STEPHEN JOSEPH SHUTTLEWORTH,ELSA AMANDINE DECHAUX,SUSSIE LERCHE KRINTEL,STEPHEN PRICE,JONATHAN MARTIN LARGE,EDWARD MCDONA
申请号：
BRPI0810646
公开号：
BRPI0810646A2
申请日:
2008.04.14
申请国别(地区):
BR
年份:
2014
代理人:
摘要：
The invention provides a pyrimidine compound of formula (I): wherein R1 and R2 have any of the values defined herein； or a pharmaceutically acceptable salt thereof. The compounds are inhibitors of PI3K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behaviour associated with PI3 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
