金属触媒の含有量が少ない生体内分解吸収性高分子及びその製法
- 专利权人:
- グンゼ株式会社
- 发明人:
- 山内 康治,島本 偉志,大谷 斉,高橋 佳丈
- 申请号：
- JP2010251692
- 公开号：
- JP5208184B2
- 申请日:
- 2010.11.10
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide an in vivo degradable and absorbable polymer, which has an extremely low metal catalyst content and is safe while maintaining desired properties suitable for medical implants or the like, and to provide a method for reducing a metal catalyst content in the in vivo degradable and absorbable polymer usable on an industrial scale.
SOLUTION: The in vivo degradable and absorbable polymer has less than 1 ppm calculated as metal of a metal catalyst content contained in the polymer. The method for reducing a metal catalyst content in the in vivo degradable and absorbable polymer comprises cleaning the in vivo degradable and absorbable polymer, containing a metal catalyst with a solution containing an organic acid. The method for producing the in vivo degradable and absorbable polymer, having a reduced metal catalyst content, comprises copolymerizing a lactide with &epsi-caprolactone in the presence of a metal catalyst to produce the in vivo degradable and absorbable polymer and cleaning the in vivo degradable and absorbable polymer with a solution containing an organic acid.
COPYRIGHT: (C)2011,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
