金属触媒の含有量が少ない生体内分解吸収性高分子の製法
- 专利权人:
- グンゼ株式会社
- 发明人:
- 有村 英俊,高橋 佳丈
- 申请号：
- JP2006178808
- 公开号：
- JP5354844B2
- 申请日:
- 2006.06.28
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a manufacturing method of an in-vivo decomposable and absorbable polymer that is safe and has a very low metal catalyst content while retaining desired properties thereof suitable for medical implants and the like, and to provide a method applicable on an industrial scale for reducing a metal catalyst content in the in-vivo decomposable and absorbable polymer.
SOLUTION: The manufacturing method of the in-vivo decomposable and absorbable polymer having a metal catalyst content of less than 1 ppm in terms of the metal comprises (1) a step for manufacturing a copolymer by copolymerizing a lactide and &epsi-caprolactone in a molar ratio of 65/35 to 85/15 and (2) a step for washing the copolymer with a mixed solvent containing acetic acid and isopropanol in a volume ratio of 45/55 to 55/45 at a temperature lower than 40°C followed by drying.
COPYRIGHT: (C)2008,JPO&INPIT
- 来源网站：
- 中国工程科技知识中心
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