Devices and methods are provided for manipulating scoping devices, surgical tools, and/or tissue. An exemplary system for manipulating a scoping device can include a scoping device having a working channel, a tether extending through the working channel, and an internal coupling member attached to the tether and positioned adjacent to a distal end of the scoping device. The internal coupling member can be magnetically coupled to an external coupling member. An exemplary method for manipulating a scoping device can include inserting at least a portion of a scoping device into a body cavity and positioning an external coupling member proximate to an external surface of tissue such that the external coupling member magnetically couples through the tissue to an internal coupling member disposed within the body cavity and attached to a tether passed through at least one working channel of the scoping device.