MERCK SHARP & DOHME CORP.;Jongwon LIM;MIchael D. ALTMAN
发明人:
Jongwon LIM,Michael D. ALTMAN
申请号：
US14904148
公开号：
US20160166576A1
申请日:
2014.07.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This invention relates to amidopyrazole compounds that are inhibitors of Interieukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment of cellular proliferative diseases. Speifically (5-methylpyridin-2-yl)-1 H-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives are disclosed for use in the method of treating inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease and cancer.
