INHIBITEURS AMIDOPYRAZOLE SUBSTITUÉS DE KINASES ASSOCIÉES AUX RÉCEPTEURS DE L'INTERLEUKINE (IRAK -4)

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

申请号：

EP14823386.9

公开号：

EP3019171B1

申请日:

2014.07.07

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This invention relates to amidopyrazole compounds that are inhibitors of Interieukin receptor-associated kinases, in particular IRAK-4, and are useful in the treatment of cellular proliferative diseases. Speifically (5-methylpyridin-2-yl)-1 H-pyrazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives are disclosed for use in the method of treating inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease and cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/