THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS;THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
GULNIK, SERGEI, V.,MITSUYA, HIROAKI,ERICKSON, JOHN, W.,GOSH, ARUN K.
申请号:
DK99931861
公开号:
DK1088098T4
申请日:
1999.06.23
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protease inhibitor. The present invention also provides a method of administering a therapeutic compound that reduces the chances of the emergence of drug resistance in therapy.