THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; REPRESENTED BY THE SECRETARY;THE UNITED STATES OF AMERICA;THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
ERICKSON, JOHN W.,GULNIK, SERGEI V.,MITSUYA, HIROAKI,GOSH, ARUN K.
申请号：
ES99931861
公开号：
ES2362404T5
申请日:
1999.06.23
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protease inhibitor. The present invention also provides a method of administering a therapeutic compound that reduces the chances of the emergence of drug resistance in therapy.
