THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
申请号:
EP10179052.5
公开号:
EP2336134B1
申请日:
1999.06.23
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention provides an assay for determining the biochemical fitness of a biochemical species in a mutant replicating biological entity relative to its predecessor. The present invention further provides a continuous fluorogenic assay for measuring the anti-HIV protease activity of protease inhibitor. The present invention also provides a method of administering a therapeutic compound that reduces the chances of the emergence of drug resistance in therapy.