LIU, BIN,SU, YANG,BIDLINGMAIER, SCOTT,BEHRENS, CHRISTOPHER R.,LEE, NAMKYUNG
申请号：
CA2960282
公开号：
CA2960282A1
申请日:
2015.09.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
In various embodiments human anti-CD46 antibodies that are internalizing and enter tumor cells via the macropinocytosis pathway are provided, as well as antibody-drug conjugates (ADCs) developed from these antibodies for diagnostic and/or therapeutic targeting of CD46-overexpressing tumors.
