Bin Liu,Yang Su,Scott Bidlingmaier,Christopher R. Behrens,Namkyung Lee
申请号：
US16691417
公开号：
US20200199245A1
申请日:
2019.11.21
申请国别(地区):
US
年份:
2020
代理人:
摘要：
In various embodiments human anti-CD46 antibodies that are internalizing and enter tumor cells via the macropinocytosis pathway are provided, as well as antibody-drug conjugates (ADCs) developed from these antibodies for diagnostic and/or therapeutic targeting of CD46-overexpressing tumors.
