Liu, Bin,Su, Yang,Bidlingmaier, Scott,Behrens, Christopher R.,Lee, Namkyung
申请号：
AU2015315006
公开号：
AU2015315006A1
申请日:
2015.09.10
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
In various embodiments human anti-CD46 antibodies that are internalizing and enter tumor cells via the macropinocytosis pathway are provided, as well as antibody-drug conjugates (ADCs) developed from these antibodies for diagnostic and/or therapeutic targeting of CD46-overexpressing tumors.
