Shah, Navnit Hargovindas,Page, Susanne,Ahmed, Hashim A
申请号：
NO20081325
公开号：
NO340473B1
申请日:
2008.03.13
申请国别(地区):
NO
年份:
2017
代理人:
摘要：
The invention relates to a process for preparing a pharmaceutical tablet composition which comprises an active pharmaceutical ingredient of formula I wherein the definitions are described in claim 1, or pharmaceutically acceptable acid addition salts thereof and a water soluble poloxamer in which the compound of formula I and the water soluble poloxamer are processed by hot melt extrusion, and then the hot melt extrudate is mixed with other ingredients to form a tablet, that is optionally coated with a composition comprising an immediate release film coating system and purified water. The invention also relates to such pharmaceutical compositions and hot melt extrudates.
