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A CELL MEDIATED IMMUNE RESPONSE ASSAY WITH ENHANCED SENSITIVITY
专利权人:
CELLESTIS LIMITED
发明人:
BOYLE, JEFF
申请号:
EP20120804281
公开号:
EP2726883(A1)
申请日:
2012.06.27
申请国别(地区):
欧洲专利局
年份:
2014
代理人:
摘要:
This disclosure relates generally to the field of immunological-based diagnostic assays including an assay to measure cell-mediated immunoresponsiveness. The present disclosure teaches diagnosis of a subject's exposure to an antigen based on cell-mediated immunoresponsiveness with enhanced sensitivity. Lymphocytes from a subject are contacted with at least a first set of peptides comprising at least one peptide of from 7 to 14 amino acid residues in length and a second set comprising at least one peptide of 16 amino acid residues or greater and the presence or elevation of an immune molecule is detected. The assay contemplated herein is capable of integration into standard pathology architecture to provide a diagnostic reporting system and to facilitate point of care clinical management.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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