Cloned DNA encoding a UDP-GalNAc: Polypeptide, N-acetylgalactosaminyltransferase

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专利权人:

PHARMACIA & UPJOHN COMPANY

发明人:

ELHAMMER, AKE P.,HOMA, FRED L.

申请号：

US19970967506

公开号：

US6096512(A)

申请日:

1997.11.11

申请国别(地区):

美国

年份:

2000

代理人:

摘要：

The present invention relates to a method for the isolation and expression of a glycosyltransferase enzyme for use in the synthesis of oligosaccharide or polysaccharide structures on glycoproteins, glycolipids, or as free molecules. The gene coding for the enzyme N-acetylgalactosaminyltransferase and the polypeptide sequence of the acceptor peptide for the enzyme N-acetylgalactosaminyltransferase have been isolated and used for the control of glycosylation of a protein.

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