This invention provides a novel delivery means that enables efficient delivery of an active ingredient to a target cell. Such novel delivery means is a liposome for topical administration that consists of dioleylphosphatidylethanolamine (DOPE), phosphatidylcholine, and cationic lipid, that is not modified with PEG, and that is free of cholesterol.本發明之目的在於提供一種可將活性成分有效率地傳遞至標靶細胞之新穎傳遞方法。本發明係一種局部投予用脂質體,其包含二油醯磷脂醯乙醇胺(DOPE)、磷脂醯膽鹼及陽離子性脂質,未經PEG修飾,且不含膽固醇。