In order to provide a new delivery means capable of effectively delivering an active ingredient to target cells, the present invention provides lipoplex containing: RNAi molecules and dioleoylphosphatidylethanolamine (DOPE), a phosphatidylcholine, and a cationic lipid, and an industrial production method therefor.本發明之目的在於提供一種能夠將活性成分有效率地傳遞至標的細胞之新傳遞手段。本發明係一種包含二油基磷脂醯乙醇胺(DOPE)、磷脂醯膽鹼、及陽離子性脂質以及RNAi分子之脂質複合體以及其工業上之製造方法。