Aminopirimidinas as inhibitors of Syk

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专利权人:

MERCK SHARP & DOHME CORP;MERCK CANADA INC

发明人:

ALTMAN, MICHAEL, D.,ANDRESEN, BRIAN, M.,ARRINGTON, KENNETH, L.,CHILDERS, KALEEN, KONRAD.,DI FRANCESCO, MARIA, EMILIA.,DONOFRIO, ANTHONY.,ELLIS, JOHN, MICHAEL.,FISCHER, CHRISTIAN.,GUERIN, DAVID, JOSEPH

申请号：

CR20120331

公开号：

CR20120331A

申请日:

2012.06.18

申请国别(地区):

CR

年份:

2012

代理人:

摘要：

The present Invention Provides New pyrimidine amides of formula (i) that are potent inhibitors of Spleen Tyrosine Kinase and are useful in the treatment and Prevention of diseases mediated by the Enzyme, such as rheumatoid arthritis, Asthma, COPD and 5.La presente invención proporciona nuevas pirimidina amidas de fórmula (I) que son potentes inhibidores de la tirosina quinasa del bazo y son útiles en el tratamiento y prevención de enfermedades mediadas por dicha enzima, tales como asma, COPD y artritis 5 reumatoide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/