FISCHER, CHRISTIAN,GAUTHIER, JACQUES YVES,MACHACEK, MICHELLE R.,OTTE, RYAN D.,COTE, BERNARD,NORTHRUP, ALAN B.,DI FRANCESCO, MARIA EMILIA,PETROCCHI, ALESSIA,TROTTER, B. WESLEY,BURCH, JASON,ALTMAN, MICH
申请号：
MX2012007154
公开号：
MX2012007154A
申请日:
2010.12.15
申请国别(地区):
MX
年份:
2012
代理人:
摘要：
The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis.La presente invención proporciona nuevas pirimidin aminas de fórmula (I) que son potentes inhibidores de la tirosina cinasa del bazo, y son útiles en el tratamiento y prevención de enfermedades mediadas por dicha enzima, tales como asma, COPD y artritis reumatoide.
