GUAY, DANIEL,GAUTHIER JACQUES YVES,OTTE,, RYAN, D.,ARRINGTON, KENNETH L.,COTE, BERNARD,NORTHRUP, ALAN B.,DI FRANCESCO, MARIA EMILIA,TROTTER, B., WESLEY,ALTMAN, MICHAEL D,ANDRESEN, BRIAN M,CHILDERS, KA
申请号：
ECSP12011982
公开号：
ECSP12011982A
申请日:
2012.06.19
申请国别(地区):
EC
年份:
2012
代理人:
摘要：
The present Invention Provides New pyrimidine amines of formula (i) that are potent inhibitors of Spleen tyrosine kinase, and are useful in the treatment and Prevention of diseases mediated by the Enzyme, such as Asthma, COPD, and rheumatoid arthritis.La presente invención proporciona nuevas pirimidina aminas de fórmula (I) que son potentes inhibidores de la tirosina quinasa del bazo, y son útiles en el tratamiento y prevención de enfermedades mediadas por dicha enzima, tales como asma, COPD y artritis reumatoide.
