Icotinib hydrochloride, compound, crystallographic form, concomitant drug and its use

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专利权人:

ベータ・ファーマ・インコーポレイテッド

发明人:

王 印祥,グオジアン・シエ,丁 列明,譚 芬来,胡 云雁,何 偉,チャールズ・デイビス,ドン・チャン,アイ・ハイマ,韓 斌,龍 偉,劉 勇

申请号：

JP2011516948

公开号：

JP5719770B2

申请日:

2009.07.07

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

The invention relates to 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, its therapeutic usage for treatment of diseases mediated by EGFR kinase and its combinatory therapeutic usage together with other therapeutic agents. The invention also provides synthetic methods for preparation of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, and the relevant synthetic intermediates for synthesis of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/