ICOTINIB HYDROCHLORIDE, SYNTHESIS, CRYSTALLOGRAPHIC FORM, MEDICAL COMBINATION, AND USES THEREOF

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专利权人:

发明人:

申请号：

EP09793788.2

公开号：

EP2392576B1

申请日:

2009.07.07

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention relates to 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, its therapeutic usage for treatment of diseases mediated by EGFR kinase and its combinatory therapeutic usage together with other therapeutic agents. The invention also provides synthetic methods for preparation of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride, its new crystalline forms, and the relevant synthetic intermediates for synthesis of 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crown-quinazoline hydrochloride.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/