ICOTINIB HYDROCHLORIDE (4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crownquinazoline hydrochloride), SYNTHESIS, CRYSTALLOGRAPHIC FORM, MEDICAL COMBINATION, AND USES THEREOF

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专利权人:

BETA PHARMA; INC

发明人:

WANG, YINXIANG,DING, LIEMING,TAN, FENLAI,HU, YUNYAN,HE, WEI,HAN, BIN,LONG, WEI,LIU, YONG,XIE, GUOJIAN,AI, HAIMA,DAVIS, CHARLES,ZHANG, DON

申请号：

NZ59033409

公开号：

NZ590334A

申请日:

2009.07.07

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is 4-[(3-ethynylphenyl)amino]-6,7-benzo-12-crownquinazoline hydrochloride, known as icotinib hydrochloride, and new crystalline forms thereof. Also disclosed are methods for preparing icotinib hydrochloride, the XRPD diffraction pattern of the new crystalline forms, pharmaceutical compositions containing the compound, use of the compound for the treatment of cancer and the intermediates of the compound.

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中国工程科技知识中心

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