A blood control valve (40) for use in a ported catheter adapter (20), the valve comprising a flexible tube having a proximal opening (42), a distal membrane (44), and an inner cavity extending therebetween, the valve comprising an outer surface having a diameter that is approximately equal to an inner diameter of the ported catheter adapter, whereby the valve is configured to be retained within the catheter adapter via a friction fit, the outer surface further having a length sufficient to form a seal between a lumen (26) of the catheter adapter and a pathway (32) of a side port (30) of the ported catheter adapter, whereby the outer surface prevents fluid communication between the side port and the lumen, and wherein the distal membrane divides the lumen of the ported catheter adapter into a proximal chamber (70) and distal chamber (80) when interference fit into the lumen.