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PHOSPHOLIPID-ANALOGOUS COMPOUNDS
专利权人:
Hans-Jörg EIBL
发明人:
Hans-Jörg EIBL
申请号:
US13084876
公开号:
US20120009246A1
申请日:
2011.04.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Phospholipid-analogous compounds of the general formula (I)in which a isb iswhere R1 and R2 are, independently of one another, hydrogen, a saturated or unsaturated acyl or alkyl radical which can optionally be branched or/and substituted, where the total of the carbon atoms in the acyl and alkyl is 16 to 44 C atoms,s is an integer from 0 to 8,c is a radical of a primary or secondary alcohol of the formula RO—, where R is a saturated or unsaturated alkyl radical, mainly with cis double bond, of froth 12 to 30 carbon atoms,n is an integer from 2 to 8,R3 a can be 1,2-dihydroxypropyl orb can be alkyl with 1 to 3 C atoms when z is >;0 orc can be alkyl with 1 to 3 carbon atoms when n≠2 and z=0,m is 1 or 2,x is an integer from 0 to 8,y is 1 for z=1 to 5 or is 1 to 4 for z=1z is an integer from 0 to 5,are novel and are suitable as liposome constituents, solubilizers and pharmaceuticals.
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