Young Kwan Kim,Myoung Yeol Kim,Sang Yun Park,Ok Ku Park,Vasily Artemov,Sang Dae Lee,Hyun Woo Joo,Eun Sil Choi
申请号：
US14440495
公开号：
US09447044B2
申请日:
2013.11.05
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to thioaryl derivatives of Formula 1 as defined in the specification, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The thioaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in macrophages, pancreas cells, etc. due to anti-inflammatory action, and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, inflammation, obesity, non-alcoholic fatty liver, steatohepatitis or osteoporosis.
