KIM, Young Kwan,PARK, Sang Yun,JOO, Hyun Woo,CHOI, Eun Sil
申请号：
AU2017203392
公开号：
AU2017203392A1
申请日:
2017.05.19
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
#$%^&*AU2017203392A120170608.pdf#####BIARYL DERIVATIVES AS GPR120 AGONISTS ABSTRACT The present invention relates to biaryl derivatives of Formula 1, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The biaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in the liver or in muscle due to anti-inflammatory action in macrophases, lipocytes, etc., and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, obesity, non-alcoholic fatty liver, steathohepatitis, osteoporosis or inflammation.
