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N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate having a specific particle size distribution range and a specific surface area range for use in pharmaceutical formulations.
专利权人:
AiCuris GmbH & Co. KG
发明人:
Schwab, Wilfried,Birkmann, Alexander,Paulus, Kerstin,Vogtli, Kurt,Haag, Dieter,Maas, Stephan,Ruepp, Kristian
申请号:
AU2012314473
公开号:
AU2012314473A1
申请日:
2012.09.26
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to the crystalline mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acet-amide in a definite particle size distribution and a specific surface area range, which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions, as well as to pharmaceutical compositions containing said N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate having the afore-mentioned particle size distribution and specific surface area range.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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