ANDREAS LENDER,ALFONS GRUNENBERG,BIRGIT KEIL,JOACHIM REHSE,WILFRIED SCHWAB,ALEXANDER BIRKMANN,KURT VOGTLI,DIETER HAAG
申请号：
IL23440514
公开号：
IL234405A
申请日:
2014.09.01
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
The present invention relates to the crystalline mesylate monohydrate salt of N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide in a definite particle size distribution and a specific surface area range, which has demonstrated increased long term stability and release kinetics from pharmaceutical compositions, as well as to pharmaceutical compositions containing said N-[5-(aminosulfonyl)-4-methyl-1,3-thiazol-2-yl]-N-methyl-2-[4-(2-pyridinyl)phenyl]acetamide mesylate monohydrate having the afore-mentioned particle size distribution and specific surface area range.
