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TREATMENT USING CHIMERIC RECEPTOR T CELLS INCORPORATING OPTIMIZED POLYFUNCTIONAL T CELLS
- 专利权人:
- KITE PHARMA; INC.
- 发明人:
- ROSSI, John,BOT, Adrian
- 申请号：
- SG11201908980P
- 公开号：
- SG11201908980PA
- 申请日:
- 2018.04.03
- 申请国别(地区):
- SG
- 年份:
- 2019
- 代理人:
- 摘要：
- ANTICD CAR scFv (FMC63) HINGE/ TRANSMEMBRANE BLOOD CELLS REMOVED FROM PATIENT SIGNAL 2: CD28 GENETIC MODIFICATION OFT CELLS FIG. 1A SIGNAL 1: CD31； 4RE-INF6ON, CAR-T PRODUCT BIOMARKER PATIENT RECEIVES ANALYSIS CAR-T CELLS FIG. 1B CAR-T CELLS El 0 El 0 0 0 0 00 ▪ CO O 0 030 FIG. 1C K562-CD19 K562-NGFR (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 October 2018 (11.10.2018) WIPO I PCT onolomolmomll Ammo oimIE (10) International Publication Number WO 2018/187332 Al N co C (51) International Patent Classification: A61K 39/00 (2006.01) GO1N 33/50 (2006.01) C07K 16/28 (2006.01) (21) International Application Number: PCT/US2018/025888 (22) International Filing Date: 03 April 2018 (03.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/481,003 03 April 2017 (03.04.2017) US (71) Applicant: KITE PHARMA, INC. [US/US]； 2225 Col- orado Avenue, Santa Monica, CA 90404 (US). (72) Inventors: ROSSI, John, M.； c/o Kite Pharma, Inc., 2225 Colorado Avenue, Santa Monica, CA 90404 (US). BOT, Adrian, I.； c/o Kite Pharma, Inc., 2225 Colorado Avenue, Santa Monica, CA 90404 (US). (74) Agent: BARBIC, Andrej et al.； Proskauer Rose LLP, One International Place, Boston, MA 02110 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, fo
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
