MULTIMERIC OLIGONUCLEOTIDES HAVING DECREASED KIDNEY CLEARANCE

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专利权人:

MPEG LA; LLC

发明人:

BROWN, Jonathan,VORNLOCHER, Hans-Peter,NEUMAN, Kristin,HADWIGER, Philipp

申请号：

SG11201906728T

公开号：

SG11201906728TA

申请日:

2018.02.06

申请国别(地区):

SG

年份:

2019

代理人:

摘要：

HONH HO HO NH (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 09 August 2018 (09.08.2018) W I PO I PCT o °nolo olommoollmoiliflo oimIE (10) International Publication Number WO 2018/145086 Al (51) International Patent Classification: A61K 31/7105 (2006.01) A61K 48/00 (2006.01) A61K 31/712 (2006.01) C07H 21/02 (2006.01) A61K 31/713 (2006.01) C07H 21/04 (2006.01) (21) International Application Number: PCT/US2018/017062 (22) International Filing Date: 06 February 2018 (06.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/455,231 06 February 2017 (06.02.2017) US 62/522,363 20 June 2017 (20.06.2017) US 62/561,853 22 September 2017 (22.09.2017) US (71) Applicant: MPEG LA, LLC [US/US]； 5425 Wisconsin Avenue, Suite 801, Chevy Chase, MD 20815 (US). (72) Inventors: NEUMAN, Kristin, K.H.； 10 Sackett Drive, Larchmont, NY 10538 (US). BROWN, Jonathan, Miles； Mpeg LA, LLC, 5425 Wisconsin Avenue, Suite 801, Chevy Chase, MD 20815 (US). VORNLOCHER, Hans-peter； Axolabs GmbH, Fritz-hornschuch-strar3e 9, D-95326 Kulm- bach (DE). (74) Agent: LINNIK, Konstantin et al.； Nutter McClennen & Fish LLP, Seaport West, 155 Seaport Boulevard, Boston, MA 02210-2604 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of reg

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