A magnetic-vibration and magnetoelectric therapy device, comprising an upper computer and a lower computer; the upper computer is used to send control instructions to the lower computer, and the lower computer is used to output stimulation signals acting on a human body based on the control instructions. The lower computer comprises a control unit, a magnetic vibration unit, a magnetoelectric unit and an electrical stimulation unit; the control unit is connected with the magnetic vibration unit, the magnetoelectric unit and the electrical stimulation unit respectively, the magnetic vibration unit is used to generate a vibrating magnetic field acting on a human body, the magnetoelectric unit is used to generate a vibrating rotating magnetic field acting on a human body, and the electrical stimulation unit is used to generate electrical stimulation signals acting on a human body. The device can be used to treat chronic prostatitis.