Disclosed is a compound Chinese medicine extract used for preventing and treating arteriosclerosis, which comprises the following active components: ceryl alcohol, beta-sitosterol, hexacosanic acid, atractylenolide Ⅲ, oleanolic Acid, berberine, jatrorrhizine, coptisine, salvianic acid A, salvianolic acid B, cyclotetracosane, 9,12-linoleic acid, 5,7-dimethoxycoumarin, Specnuezhenide, ginsenoside Rb1 and Rg1, notoginsenoside R1, eucommiol, etc. The said extract is prepared from the raw medicines of danshen root, glossy privet fruit, coptis root, Japanese thistle herb or root, eucommia bark, largehead atractylodes rhizome, panax notoginseng, and bergamot, through mixing effective fractions extracted by organic solvents with different polarity from the total extract of the raw medicine which is extracted by C1-3 alcohol and/or water. Because of elimination of large quantities of noneffective components, the content of the effective components increases largely, and the influence of noneffective components to product processing and formulation quality is decreased. The preparation method is stable and available for mass production with controllable product quality.Linvention concerne un extrait composé de la médecine chinoise, destiné à prévenir et à traiter lartériosclérose et qui comprend les principes actifs suivants: lalcool cérylique, le bêta-sitostérol, lacide hexacosanique, latractylénolide Ⅲ, lacide oléanolique, la berbérine, la jatrorrhizine, la coptisine, lacide salvianique A, lacide salvianolique B, le cyclotétracosane, lacide 9,12-linoléique, la 5,7-diméthoxycoumarine, le Specnuezhenide, le ginsenoside Rb1 et Rg1, le notoginsenoside R1, leucommiol, etc. Cet extrait est préparé à partir de matières premières médicamenteuses de racine de danshen, de fruit de troène, de racine de coptis, de la partie aérienne ou de la racine du chardon japonais, de lécorce deucommia, de rhizome datractylode à grosse tête, de panax notoginseng et de bergamote, par le mélange des