Kirste Joanne Mellish;David Ian Vernon;Cassandra Claire O'Grady;Richard George Tunstall;David John Howard Roberts;Stanley Beames BROWN;John Griffiths
发明人:
Stanley Beames BROWN,Cassandra Claire O'Grady,John Griffiths,Kirste Joanne Mellish,Richard George Tunstall,David John Howard Roberts,David Ian Vernon,Cassandra Claire OGrady
申请号：
US13453855
公开号：
US20120302557A1
申请日:
2012.04.23
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a method of photodynamic therapy and to a method of inducing a photocytoxic effect which comprises applying to an area to be treated an effective amount of a compound of formulain which R1, R2, R3 and R4 each independently is an optionally-substituted linear, branched or cyclic hydrocarbon group, or R1 and R2 together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring or R3 and R4 together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring；and where XP− is a counteranion and P is 1, 2 or 3；except for the compounds in which —NR1R2 and —NR3R4 are the same and are selected from —N(CH3)2 or —N(CH2CH3)2； andexposing the area to light to activate the compound.
