Disclosed are bis(thio-hydrazide amide) disalts, which are represented byStructural Formula (I) Y is a covalent bond or a substituted or unsubstitutedstraight chained hydrocarbyl group. R1-R4 are independently -H, an aliphaticgroup, a substituted aliphatic group, an aryl group or a substituted arylgroup, or R1 and R3 taken together with the carbon and nitrogen atoms to whichthey are bonded, and/or R2 and R4 taken together with the carbon and nitrogenatoms to which they are bonded, form a non-aromatic heterocyclic ringoptionally fused to an aromatic ring. Z is -O or -S. M+ is a pharmaceuticallyacceptable monovalent cation and M2+ is a pharmaceutically acceptable divalentcation. Also, disclosed are pharmaceutical compositions comprising a bis(thio-hydrazide amide) disalt described above. Further disclosed are methods oftreating a subject with cancer. The methods comprise the step of administeringan effective amount of a bis(thio-hydrazide amide) disalt described above.
