SALFORD, LEIF,PERSSON, BERTIL,SJOEGREN, HANS, OLOV,WIDEGREN, BENGT
申请号:
EP08753969
公开号:
EP2164500A4
申请日:
2008.05.26
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention relates to the use of 1-(&bgr;-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one derivative or mimetic or an analogue, derivatives, metabolites, variants or salts thereof for the manufacturing of a medicament to increase the amount of Indoleamine 2,3-dioxygenase (IDO) production in order to induce immunological tolerance as well as a method of treating a mammal in need thereof.