Leif G. Salford,Bertil Persson,Hans Olov Sjögren,Bengt Widegren
申请号:
US14940657
公开号:
US20160068809A1
申请日:
2015.11.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to the use of 1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one derivative or mimetic or an analogue, derivatives, metabolites, variants or salts thereof for the manufacturing of a medicament to increase the amount of Indoleamine 2,3-dioxygenase (IDO) production in order to induce immunological tolerance as well as a method of treating a mammal in need thereof.