Fei LIU,Cuixia ZHANG,Chenggang LIN,Chunyan ZHOU,Pan CHEN,Wei WANG,Lulu WANG
申请号:
US15972500
公开号:
US20180250278A1
申请日:
2018.05.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a donepezil derivative of general formula (I) or a pharmaceutically acceptable salt thereof, wherein R in the formula is as disclosed herein; and a method for preparation thereof; and a composition comprising an effective amount of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof. The present invention also relates to use of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof in preparing a medicament for treating a disease resulted from an abnormality in acetylcholinesterase activity.