A NOVEL PROCESS FOR THE PREPARATION OF PROSTAGLANDINS AND INTERMEDIATES THEREOF

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专利权人:

BIOCON LIMITED

发明人:

ASWATHANARAYANAPPA, CHANDRASHEKAR,SRINIVAS, PULLELA, VENKATA,KANGATH, DIVYA,SOUNDARARAJAN, THILAK, GREGORY,PRASAD, ANEGONDI, SREENIVASA,RAGHAVENDRAN, SURIYAN, MASINAICKENPATTY

申请号：

EP09851063

公开号：

EP2496553A4

申请日:

2009.12.21

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

This invention relates to novel process for the preparation of prostaglandin compounds having formula (K), wherein R is selected from the group consisting of C1-C7 alkyl C7-C17 aralkyl wherein the aryl group is unsubstituted or substituted with one to three substituents selected from the group consisting of C1-C6 alkyl, halo and CF3 and (CH2)nOR2 wherein n is from 1 to 3 and R2 represents a C6-C10 aryl group which is unsubstituted or substituted with one to three substituents selected from the group consisting of C1-C6 alkyl, halo and CF3 and R1 is selected from OR3 and NHR3 wherein R3 is C1-C6 alkyl, H and dashed lines represents a double bond or a single bond, is disclosed. Novel intermediates are also disclosed.

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