A system for imploding leukemia cells of a patient includes (a) a first vessel for containing a volume of blood received from the patient, and (b) drive circuitry cooperatively coupled with at least one transducer to produce ultrasound energy that spatially decoheres and disperses throughout the volume, to implode the leukemia cells throughout the volume via absorption of the ultrasound energy by the leukemia cells. The transducer may be an immersible transducer configured to be immersed in the blood. The system may include a second vessel for containing a liquid, within which the ultrasound energy is decohered and dispersed and from which at least a portion of the ultrasound energy is transmitted to the first vessel to implode the leukemia cells.