T cells with increased immunosuppression resistance

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专利权人:

Adaptimmune Limited

发明人:

Bruno Laugel,Kathrin Skibbe

申请号：

US15713464

公开号：

US09976121B2

申请日:

2017.09.22

申请国别(地区):

US

年份:

2018

代理人:

摘要：

This invention relates to the treatment of cancer in an individual by administration of a population of modified T cells that express a recombinant cAMP phosphodiesterase (PDE) or a fragment thereof and an antigen receptor which binds specifically to cancer cells in the individual. Populations of modified T cells and methods of producing populations of modified T cells are provided, along with pharmaceutical compositions and methods of treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/