Akita University;Institute of Immunology Co., Ltd.
发明人:
Akira SHIOTA,Tatsuya MIZOROKI,Yuki MORITOKI
申请号:
US15569545
公开号:
US20180295818A1
申请日:
2016.04.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
It is an object of the present invention to provide a transgenic non-human animal, which can appropriately evaluate properties, pharmacological effects and safety of a molecular targeted substance or targeted drug to a human specific molecule, and to provide a method for producing the transgenic non-human animal, which comprises a gene encoding a human specific molecule and a gene encoding a human Fcγ receptor family, both genes being introduced in the animal, thereby expressing the gene encoding a human specific molecule and the gene encoding a human Fcγ receptor family.