The present invention discloses a lens and frame assembly structure of a goggle, which comprises lenses with tenons and frames with mortises. After the lenses are inserted into the grooves of the frames, the tenons of the lenses are inserted into the mortises of the frames, so as to firmly secure the lenses with the frames. When the goggle according to the present invention is subjected to torsion or impact, the lenses will not be easily fallen out.本發明係揭露一種護目鏡之鏡片與鏡框組合結構,包括具有卡榫之鏡片以及具有插孔之鏡框。此鏡片插入鏡框之嵌槽後,鏡片之卡榫插入鏡框之插孔,藉此強化鏡片固定於鏡框上,當本發明之護目鏡受到扭曲或衝擊時,鏡片亦不易掉落。100‧‧‧鏡片110‧‧‧卡榫200‧‧‧鏡框210‧‧‧插孔220‧‧‧嵌槽231‧‧‧上框體232‧‧‧下框體400‧‧‧開口211‧‧‧第一插孔開口212‧‧‧第二插孔開口