KLINGE BIOPHARMA GMBH;FORMYCON AG;SIO2 MEDICAL PRODUCTS, INC.
发明人:
BROCKMEYER, CARSTEN,WEIKART, CHRISTOPHER,BENNETT, MURRAY STEPHEN,GIRAUD, JEAN-PIERRE,STRUNGMANN, THOMAS
申请号:
CA3005117
公开号:
CA3005117A1
申请日:
2016.11.18
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A pre-filled pharmaceutical package comprising a liquid formulation of a VEGF-antagonist, for example Ranibizumab, in a pre-filled pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer. Stability performance of the VEGF-antagonist packaged in the coated COP vessel comparable to or better than glass was obtained.