Detachment of a medical device from a delivery assembly can be electrolytic and provide flushing with an infusion of fluid to enhance detachment procedures. A device providing such capabilities can include a catheter having a lumen; a core member extending through the lumen; an implant attached to the core member by an electrolytic detachment junction, the detachment junction being radially adjacent to an electrode within the lumen; and a pump in fluid communication with a distal end region of the catheter through the lumen, the pump being configured to provide a flow of a fluid between the return electrode and the detachment junction. The implant can be positioned at a target location. The electrode can be positioned radially adjacent to the detachment junction. A voltage potential is applied while a fluid is flushed between the detachment junction and the electrode through the lumen of the catheter.