Detachment of a medical device from a delivery assembly can be electrolytic and provide flushing with an infusion of fluid to enhance detachment procedures. A device providing such capabilities can include a catheter having a lumen a core member extending through the lumen an implant attached to the core member by an electrolytic detachment junction, the detachment junction being radially adjacent to an electrode within the lumen and a pump in fluid communication with a distal end region of the catheter through the lumen, the pump being configured to provide a flow of a fluid between the return electrode and the detachment junction. The implant can be positioned at a target location. The electrode can be positioned radially adjacent to the detachment junction. A voltage potential is applied while a fluid is flushed between the detachment junction and the electrode through the lumen of the catheter.